Integrated Regulation from ENCODE Tracks
整合ENCODE项目的“基因表达调控信息” 选项卡
Tranion：Tranion Levels Assayed by RNA-seq on 9 Cell Linesfrom ENCODE
ENCODE项目9种细胞系的 RNA-seq实验的转录表达水平数据集
Layered H3K4Me1：H3K4Me1 Mark (Often Found Near Regulatory Elements) on 7 cell lines from ENCODE
ENCODE项目的7种细胞系的 H3K4Me1抗体标签的ChIP-Seq数据集(3 组蛋白4位赖氨酸单甲基化；基因组DNA结合区为调控单元)
Layered H3K4Me3：H3K4Me3 Mark (Often Found Near Promoters) on 7 cell lines from ENCODE
ENCODE项目的7种细胞系的 H3K4Me3抗体标签的ChIP-Seq数据集(3 组蛋白4位赖氨酸3甲基化；通常发现在启动子附近)
Layered H3K27Ac H3K27Ac Mark (Often Found Near Regulatory Elements) on 7 cell lines from ENCODE
ENCODE项目的7种细胞系的H3K27Ac抗体标签的ChIP-Seq数据集(3 组蛋白27位赖氨酸乙酰化；基因组DNA结合区为调控单元)
DNase ClustersDNase I Hypersensitivity Peak Clusters from ENCODE (95 cell types)
ENCODE项目的95种细胞系的 DNase抗体标签的ChIP-Seq数据峰图集合（DNA核酸酶超敏感区）
DNase Signal DNase I Hypersensitivity Signal Colored by Similarity from ENCODE
ENCODE项目相关的DNase抗体标签的ChIP-Seq数据信 彩图（DNA核酸酶超敏感区）
DNase HSDNase I Hypersensitivity in 95 cell types from ENCODE
ENCODE项目的95种细胞系的 DNase抗体标签的ChIP-Seq数据集（DNA核酸酶超敏感区）
Deion
选项卡描述
These tracks contain information relevant to the regulation of tranion from the ENCODE Project.
该选项卡包含了ENCODE项目有关 基因转录调控相关的信息。
The Tranion track shows tranion levels assayed by sequencing of polyadenylated RNA from a variety of cell types.
转录表达选项卡可显示 不同的细胞类型的RNA转录表达水平。
The Layered H3K4Me1 and Layered H3K27Ac tracks show where modification of histone proteins is suggestive of enhancer and, to a lesser extent, other regulatory activity.
H3K4Me1和H3K27Ac为抗体标签的ChIP-Seq数据选项卡可显示 组蛋白修饰的情况，暗示基因组DNA增强子的位置，在较低相关性上可标明其他类别的调控行为。
These histone modifications, particularly H3K4Me1, are quite broad. The actual enhancers are typically just a small portion of the area marked by these histone modifications.
这些组蛋白修饰模式: 尤其是H3K4Me1非常普遍：实际的增强子通常是只有一小部分区域结合这组蛋白修饰模式。
The Layered H3K4Me3 track shows a histone mark associated with promoters.
H3K4Me3为抗体标签的ChIP-Seq数据选项卡显示了 组蛋白标记与启动子的相关结合区域。
The DNase I Hypersensitivity tracks indicate where chromatin is hypersensitive to cutting by the DNase enzyme, which has been assayed in a large number of cell types.
DNase活性结合区域：染色质高度敏感区域容易被DNase酶酶解，已经在大量的细胞类型中得到验证。
Regulatory regions, in general, tend to be DNase-sensitive, and promoters are particularly DNase-sensitive.
基因调控区：一般来说,往往是DNase敏感结合的区域、尤其是启动子。
These tracks complement each other and together can shed much light on regulatory DNA.
上叙的项目是相关可重叠的，可共同结合同一基因组DNA调控区域。
The histone marks are informative at a high level, but they have a resolution of just ~200 bases and do not provide much in the way of functional detail.
组蛋白修饰的标记信息在一个信息含量非常高的现象，本选项卡精度只是大约在200bp左右和没有提供太多的基因功能调控的细节。
The DNase hypersensitivity assay is higher in resolution at the DNA level and can be done on a large number of cell types since it’s just a single assay.
DNase敏感性的ChIP实验 是在检测可调控DNA区域更高的精度，已经经过大量的细胞类型测试。
At the functional level, DNase hypersensitivity suggests that a region is very likely to be regulatory in nature, but provides little information beyond that.
在基因功能层面，DNase敏感性的ChIP实验：这种基因组DNA接合区很可能是基因调控的区域，除此之外也有一些信息可以参考。
Though each assay has its strengths and weaknesses, the fact that all of these assays are relatively independent of each other gives increased confidence when multiple tracks are suggesting a regulatory function for a region.
尽管每种实验都有其优劣；但是这些实验是彼此相对独立的，可以为确定基因组DNA的调控区域找到多维度的证据。
For additional information, please click on the hyperlinks for the individual tracks above.
更多信息：可点击上面的超链接（指的是设置项目 蓝色高亮的词）。
Also note that additional histone marks and tranion information is available in other ENCODE tracks.
其他种类的组蛋白抗体标记的ChIP-Seq数据可在其他ENCODE相关数据卡中找到
This integrative supertrack just shows a selection of the most informative data of most general interest.
原文链接为该选项卡设置页面
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